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Original Article

Serial Doppler Echocardiographic Evaluation of Anthracycline Induced Left Ventricular Dysfunction in Children

Nam Geun Heo, Myung Chul Hyun, Kun Soo Lee, Sang Bum Lee

Clin Exp Pediatr. 1993;36(2):214-222. Published online February 15, 1993

Anthracycline drugs are chemoterapeutic agents highly effective against a wide range of neoplasms. However, its administration may be complicated by cardiotoxic reactions. There is a continuum of increasing risk with increasing total dose of drug rather than an absolute cutoff point for total dose drug of that should not be exceeded under any circumstances. At the present time it appears that a...

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