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Original Article
Evaluation of theIndications of Renal Biopsy in Children with Primary Nephrotic Syndrome
Seung Ju Lee
Clin Exp Pediatr. 1996;39(12):1736-1744.   Published online December 15, 1996
Purpose : Percutaneous renal biopsy in children with primary nephrotic syndrome(NS) contributed to establish the renal pathology and clinicopathological correlation. The most common minimal change lesion(MCL) was steroid sensitive and could be predicted by clinical and laboratory findings. It was uniformly agreed that most nephrotic children who were predicted as MCL, should receive an 8 week course of prednisolone before considering renal biopsy. Early indications...
The Roles of IgG and Albumin as a Predictor of Frequent Relapse
Jae-Ho Lee, Jong-Gyun Kim
Clin Exp Pediatr. 1994;37(9):1245-1250.   Published online September 15, 1994
The etiology of nephrotic syndrome is unknown. The characterization were proteinuria, hypoalbuminemia, generalized edema and hyperlipidemia. To assess the recurrence factors in the nephrotic syncrome, we measured serum immunoglobulin(IgG, IgA, IgM), albumin, complement, cholesterol and the 24-hour total urine protein at the initial relapse of nephrotic syndrome. Each data of frequent and infrequent relapsed nephrotic syndrome were compared. In total...
A Retrospective Study on the Effect of Cyclophosphamide in Children with Minmal Change Nephrotic Syndrome.
Il Soo Ha, Kwang Wook Ko, Yong Il Kim
Clin Exp Pediatr. 1987;30(2):158-174.   Published online February 28, 1987
Thirty one children associated with biopsy-proven minimal change nephrotic syndrome with frequent relapse, were placed on cyclophosphamide, and its effect was analyzed. Cyclophosphamide was given with the dosage of 2.46±0.42 mg/kg/day for 58±7 days along with the alternate day corticosteroid. Sixty three percent of the patients showed complete remission and twenty seven percent of the patients resulted in partial remission after the treatment. Those...
Plasma Basal Cortisol Level and Its Significance in Minimal Change Neprotic syndrom.
Han Wook Yoo
Clin Exp Pediatr. 1986;29(6):644-652.   Published online June 30, 1986
Morning plasma basal cortisol levels were measured by radioimmunoassay in seventeen patients with minimal change nephrotic syndrome which was proved in fourteen patients pathologically and suggested clinically in three. These patients could be grouped as ten frequent relapsers and seven control group patients who consisted of five infrequent relapsers, one continuing nonresponder and one late responder according to response to...