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Review Article

Clinical efficacy and mechanism of probiotics in allergic diseases

Ha-Jung Kim, Hyung Young Kim, So-Yeon Lee, Ju-Hee Seo, Eun Lee, Soo-Jong Hong

Clin Exp Pediatr. 2013;56(9):369-376. Published online September 30, 2013

A complex interplay between genetic and environmental factors partially contributes to the development of allergic diseases by affecting development during prenatal and early life. To explain the dramatic increase in the prevalence of allergic diseases, the hygiene hypothesis proposed that early exposure to infection prevented allergic diseases. The hygiene hypothesis has changed to the microbial hypothesis, in which exposure to...

DOI: https://doi.org/10.3345/kjp.2013.56.9.369

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