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Original Article

Changes of Bone Metabolism Markers and Bone Mineral Density with Improvement of Thyroid Function in Children and Adolescents with Hyperthyroidism

Min Ho Jung, Choong Ho Shin, Sei Won Yang, Byung Churl Lee

Clin Exp Pediatr. 2002;45(6):743-753. Published online June 15, 2002

Purpose : Dynamics of bone mineral density(BMD) and bone metabolism in children and adolescents with hyperthyroidism have not been thoroughly investigated. The aim of this study was to study how the improvement of thyroid function with antithyroid treatment influenced bone metabolism and BMD in children and adolescents with hyperthyroidism. Methods : Serum levels of osteocalcin(OC), bone-specific alkaline phosphatase(b-ALP), and carboxyterminal telopeptide...

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