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Review Article
Disease-specific pluripotent stem cells
Hoon-Chul Kang
Clin Exp Pediatr. 2010;53(8):786-789.   Published online August 31, 2010

Induced pluripotent stem (iPS) cells are generated by epigenetic reprogramming of somatic cells through the exogenous expression of transcription factors. Recently, the generation of iPS cells from patients with a variety of genetic diseases was found to likely have a major impact on regenerative medicine, because these cells self-renew indefinitely in culture while retaining the capacity to differentiate into any...



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