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Original Article

Expression of Toll-like Receptor-2 on the Peripheral Blood Monocytes in Kawasaki Disease Patients

Dae Hwan Hwang, Jung Woo Han, Kyung Min Choi, Kyung Mi Shin, Dong Soo Kim

Clin Exp Pediatr. 2005;48(3):315-320. Published online March 15, 2005

Objective : Toll like receptor(TLR) is known to be involved in innate immunity. Many microbial antigens stimulate TLR, and as a result of intracellular signal transduction, they activate nuclear factor-kB which produces diverse inflammtory cytokines. Until now, many research topics in Kawasaki disease focused on cytokine increasement. In this study, we aim to reveal TLR increasement which might be associated...

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