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Original Article

Studies on the Prognostic Marker in Minimal Change Nephrotic Syndrome

Byoung-Soo Cho

Clin Exp Pediatr. 1993;36(7):906-912. Published online July 15, 1993

Childhood minimal change nephrotic syndrome (MCNS) is often associated with hyper-sensitivity reactions and considered to be caused by immune dysfunction. The elevated serum IgE levels and atopic symptoms have been frequently associated in these patients. The present therapy for MCNS mainly depends on corticosteroids, alkylating agents such as chlorambucil, cyclophosphamide and cyclosporin A (Cy-A). Howerver, frequent relapses and severe side effects...

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