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Review Article

Eosinophil-derived neurotoxin: a novel biomarker for diagnosis and monitoring of asthma

Chang-Keun Kim

Clin Exp Pediatr. 2013;56(1):8-12. Published online January 29, 2013

Asthma is associated with increased levels of eosinophils in tissues, body fluids, and bone marrow. Elevated levels of eosinophil-derived neurotoxin (EDN) and eosinophil cationic protein (ECP) have been noted in asthma patients. Higher levels of EDN and ECP are also associated with exacerbated asthmatic conditions. Thus, EDN, along with ECP, may aid the diagnosis and monitoring of asthma. Several groups...

DOI: https://doi.org/10.3345/kjp.2013.56.1.8

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