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Original Article

Distribution of CD4＋CD25＋ T cells and graft-versus-host disease in human hematopoietic stem cell transplantation

Dae Hyoung Lee, Nak Gyun Chung, Dae Chul Jeong, Bin Cho, Hack Ki Kim

Clin Exp Pediatr. 2008;51(12):1336-1341. Published online December 15, 2008

Purpose : This study aimed to determine the frequencies of CD4＋CD25＋ T cells in donor graft and peripheral blood CD4＋CD25＋ T cells in recipients after hematopoietic stem cell transplantation (HSCT) and their association with graft-versus-host disease (GVHD). Methods : Seventeen children who underwent HSCT were investigated. CD4＋CD25＋ T cells in samples from donor grafts and recipient peripheral blood were assessed...

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