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Original Article

Inhalation of Bronchodilator Aerosol by Metered-dose Inhaler and Spacer in Neonatal Respiratory Distress Syndrome

Hyeon-Soo Lee

Clin Exp Pediatr. 1999;42(12):1668-1675. Published online December 15, 1999

Purpose : To examine the clinical effects of two bronchodilator agents, salbutamol and ipratropium bromide, administered by metered-dose inhaler(MDIS) to preterm infants with respiratory distress syndrome(RDS) during mechanical ventilation. Methods : This study included 8 ventilated preterm infants with RDS, at a postnatal age of 1 week. The effects of single doses of salbutamol(2puffs, 200mcg) and ipratropium bromide(2 puffs, 36mcg) and...

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