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Original Article

A Study of Clinical Features of Acute Tumor Lysis Syndrome in Children

Ick-Jin Song, Young-Tak Lim

Clin Exp Pediatr. 2000;43(7):952-958. Published online July 15, 2000

Purpose : Tumor lysis syndrome is characterized by hyperuricemia, hyperphosphatemia, hyperkalemia and hypocalcemia due to destruction of tumor cells. The purpose of this study is to estimate in children the incidence, onset time, differences in outcomes between hemodialysis and conservative therapy, and predictive factor of tumor lysis syndrome before treatment with chemotherapy. Methods : Subjects were 108 children who had received...

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