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Renal Transport Proteins Involved in Urinary Concentrating Mechanism

Dong Un Kim

Clin Exp Pediatr. 2004;47(5):480-484. Published online May 15, 2004

Renal tubule and vasa recta are arranged in complex but specific anatomic relationships and the production of a concentrated urine is achieved by countercurrent multiplication mechanism in the renal medulla. This model requires that the ascending thin limb is highly permeable to NaCl but impermeable to water, while the descending thin limb is impermeable to NaCl but highly permeable to...

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