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Review Article
Cardiology
Diagnosis of coronary artery abnormalities in Kawasaki disease: recent guidelines and z score systems
Sung Hye Kim
Clin Exp Pediatr. 2022;65(9):430-438.   Published online December 17, 2021
∙ Kawasaki disease is the leading cause of acquired heart disease among children in the developed countries, and Korea has the second-highest incidence in the world.
∙ Early diagnosis and proper treatment are imperative to prevent coronary complication, and evaluation of coronary artery abnormalities is fundamental.
∙ Recent guidelines have adapted z score system for the diagnosis of coronary artery abnormalities in Kawasaki disease.
∙ Applying z score in diagnosis of coronary abnormalities has better correlation with clinical outcomes than absolute cutoff values.
∙ Calculated z scores could be different according to the z score formula, which might influence the treatment plan.
Original Article
General Pediatrics
Effect of 2–6 weeks of systemic steroids on bone mineral density in children
Athira Kuniyil, Somdipa Pal, Namrita Sachdev, Tribhuvan Pal Yadav
Clin Exp Pediatr. 2022;65(5):254-261.   Published online November 18, 2021
Question: Does steroid use for 2–6 weeks in children affect bone mineral content (BMC) or density (BMD)?
Finding: Steroid use for 2–6 weeks significantly decreased BMC and BMD of the whole body, total body less the head, lumbar spine, and distal radius. A significant negative correlation was observed among BMD, duration, and cumulative dose.
Meaning: Steroid use for 2–6 weeks in children negatively affected BMC and BMD.
Serum IgE Standardized for Age in Korean Children and Its Diagnostic Reliability in Childhood Asthma
Myung Su Lee, Eun Sun Yoo, Hye Sun Kim, Eun Ae Park, Jeong Wan Seo, Seung Joo Lee
Clin Exp Pediatr. 1996;39(3):397-403.   Published online March 15, 1996
Purpose : IgE was identified by Ishizaka as an antibody that is reacted at Type I hypersensitivity reaction, and has been used in the diagnosis of allergic disease and the differential diagnosis of extrinsic and intrinsic asthma. But there was some confusing in the diagnosis because of the broad range of measured serum IgE. Recently it was reported that serum IgE...