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In this study, we attempted to determine an optimal first dose of phenobarbital for the treatment
of seizures in the asphyxiated full term neonates.
Blood samples were obtained 2 to 48 hours after the administration of final effective loading dose
and plasma levels were determined by the EMIT system.
Four groups of neonates were studied. Six neonates (Group 1) received an intravenous loading dose
of... |