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Original Article
The Effect of Prolonged Treatment in Children with Chronic Hepatitis B with Combination of Alpha-Interferon and Acyclovir
Jeong Ok Hah, Kyoung A Lee
Clin Exp Pediatr. 1993;36(12):1701-1706.   Published online December 15, 1993
This study was conducted to evaluate the effect of prolonged treatment in children with chronic hepatitis B will combination of alpha-interferon and acyclovir. The study population consisited of & patients with chronic hepatitis B who showed histological findings compatible with chronic active hepatitis (4 cases) or chronic persistent hepatitis (3 cases) on liver biopsy and had elevated AST and ALT with...
Esophageal Varix in Children - Endoscopic Evaluation and Clinical characteristics-
Soon Young Kim, Jeong Kee Seo
Clin Exp Pediatr. 1993;36(12):1691-1700.   Published online December 15, 1993
Fifty five children with encoscopically proven esophageal varices form Jul. 1987 to Dec. 1992 were analyzed for endoscopic and clinical characteristics. The results were as follows : 1) According to etiological classification of portal hypertension in 55 cases, 35 cases showed intrahepatic causes (64%) and cases had extrahepatic causes (36%). The most common clinical manifestation on admission was hematemesis (42%) and abdominal mass...
A Clinical Study of Bronchial Asthma in Children
Seung Hee Park, Myung Ik Lee, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1993;36(9):1291-1299.   Published online September 15, 1993
This report is a clinical analysis and comparative study with previous report of bronchial asthma at National Medical Center on bronchial asthma in children who were admitted to the MP dept. of national Medical Center from January 1987 to December 1990. The results of the study were as follows: 1) The out-break ratio of bronchial asthma is 3.7% of hopitalized children which...
Neurologic Complications after Open-Heart Surgery in Children
Tae Sung Ko, Ki Joong Kim, Dong Wook Kim, Yong Seung Hwang, Yong Jin Kim, Joon Ryang Rho
Clin Exp Pediatr. 1993;36(9):1245-1257.   Published online September 15, 1993
Neurologic complications after open-heart surgery are not only relatively common but also often fatal. In order to know the clinical characteristics and carsative risk factors, we carried out the retrospective study on 655 patients who had been admitted and undergone OHS at Seoul National University Children's Hospital during 2-year period from July 1990 to June 1992. The results...
Blood Pressure Measurement of School-Aged Children in Goesan
Seong Hoon Hah
Clin Exp Pediatr. 1993;36(5):705-713.   Published online May 15, 1993
Since clinical significance of blood pressure level in childhood has been known, a several studies for the purpose of establishing normal blood pressure referce values in Korean school-aged children were performed. The author of this article measured normal blood pressure values for children in an elementary school, and two middle schools of Korean rural area using mercury sphygmomanometer. The results...
A Prospective Study of Totally Implanted Venous Access System in 19 Children with Cancer
Kyung Duk Park, Eun Sil Dong, Seong Hoon Ha, Hong Hoe Koo, Hee Young Shin, Hyo Seop Ahn, Seong Eun Jun, Gui Won Park
Clin Exp Pediatr. 1993;36(5):687-692.   Published online May 15, 1993
A totally implanted venous access system was inserted in 19 children with cancer. The devices were utilized for the administration of antineoplastic drug, parenteral fluids, antibiotics, and blood products. Total duration of implantation was 4,046 days for 23 implanted system (range 7-445 days). Complications included cather infection (0.247/100 catheter day), occlusion (0.692/100 catheter days), and dislodgement of needle (0.643/100 catheter...
Gastrofiberscopic Findings in Children Complaining of Upper Gatrointestinal Symptoms
Jeong Wan Seo
Clin Exp Pediatr. 1993;36(5):649-655.   Published online May 15, 1993
A gastrofiberscopic evaluation was performed on 65 children complaining of upper gastrointestinal symptoms who visited the pediatric department of Hanil hospital from March 1991 to September 1992. Gastrofiberscopy was done without local anesthesia of pharynx and heavy sedation. To identify H. pylori infection, biopsy specimen was taken from the gastric antrum since Feb. 1992. The specimens were examined using the rapid...
Clincal Observation on Guillain-Barré Syndrome in Children
In Cheol Park, In Seung Park, Jeh Hoon Shin, In Joon Seol, Ha Baik Lee
Clin Exp Pediatr. 1993;36(5):634-642.   Published online May 15, 1993
Clinical observation was performed on 23 children with Guillain-Barré syndrome which were hospitalized at the Pediatric ward of Han Yang University Hospital, from July 1975 through May 1991. The results were as follows: 1)The ratio of male patient to female was 2.8:1 and 47.8% of total GBS patients were between the ages 1to 5 years. 2)The highest seasonal incidence of GBS was seen...
Analysis of Foreign Body in the Children's Airway and Follow-up Study
Jae Hong Park, Chan Yung Kim
Clin Exp Pediatr. 1993;36(2):169-178.   Published online February 15, 1993
The autor analysed foreign body in the airway, divided into two groups vegetable foreign body group(VFBG) and non-vegetable foreign body group(N-VFBG), according to the nature, in 88 patients aged from 5 months to 15years who were diagnosed and treated under ventilating bronchos copy at Department of Pediatrics and Otolaryngology, Pusan National University Hospital from 1980 to 1990. Of the 88...
Statistical Analysis of the Prevalence and Trend of Obesity in Elementary School Children in Kwangju
Kyung Rae Moon, Young Bong Park
Clin Exp Pediatr. 1993;36(1):81-87.   Published online January 15, 1993
To estimate the prevalence and trend of obesity in primary school-age children, obesity survey was performed in children aged 6 to 12 years (5,226 boys and 5,048 girls) in Kwangju in 1991. Obesity was defined as overweight if more than 20 per cent above the median weight for height and age (relative weight>120%). The following results were obtained: 1) The prevalence of...
Acute Megakaryoblastic Leukemia in Children
Hong Hoe Koo, Sang Kyu Park, Eun Sil Dong, Hye Jung Park, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1993;36(1):9-16.   Published online January 15, 1993
We analyzed the clinical and laboratory features of ten children with acute megakaryoblastic leukemia (M7) and compared the findings with those reported in the literature. The diagnosis was supported by ultrastructural examination of platelet peroxidase or immunophenotyping for glycoprotein Iib/IIIa. Of the ten children, five were girls and five were boys. The median age at diagnosis was 13 months. Two...
Gastrofiberscopic Findings and Helicobacter pylori Gastritis in Children with Recurrent Abdominal Pain
Jeong Kee Seo, Je Geun Chi, Eui Chong Kim
Clin Exp Pediatr. 1992;35(12):1646-1656.   Published online December 15, 1992
Gastrofiberscopic findings and the presence of Helicobacter pylori (H. pylori) were studied prospectively in children with recurrent abdominal pain (RAP). Endoscopic findings in 707 children with RAP revealed that 243 children (34.3%) showed abnormal findings including gastritis in 16.9%, duodenitis in 10.4%, esophagitis in 5.7%, duodenal ulcer in 5.7%, and gastric ulcer in 1.1% of children with RAP. Endoscopic biopsy of...
Portal Hypertension in Children
Young Sook Kim, Ki Sup Chung
Clin Exp Pediatr. 1992;35(11):1528-1536.   Published online November 15, 1992
Portal hypertension assumes special interest in children due to the large variety of causes, the apparent difficulty of performing surgical portal systemic shunts because of the small size of vessels, the doubt still cast on the long term tolerance of portal systemic shunts and the theoretical possibility of spontaneous regression of varices with growth. Thirty cases of portal hypertension under...
Case Report
Three Cases of Listeria Infection in the Immunocompromised Children
Mee Ran Kim, Bo Young Yun, Hye Young Kang, Sung Hee Jang, Hoan Jong Lee, Yong Seung Hwang, Eui Chong Kim
Clin Exp Pediatr. 1992;35(10):1419-1426.   Published online October 15, 1992
Infection by Listeria monocytogenes, an uncommon pathogen in immunocompromised host, has been reported in neonates, pregnant women and adults with defective cell mediated immunity but not in children in Korea. It can cause sepsis, meningitis, abortion, premature labor, intrauterine fetal infection. etc. We have experienced L. monocytogenes sepsis and/or meningitis in three children under immunosuppresive therapy for lymphoma-leukemia, cytophagic histiocytic...
Original Article
Immunohistochemical Studies on Neuroendocrine Markers in Malignant Neuronal Tumors (Neuroblastoma and Ganglioneuroblastoma) in Children
Woo Yeong Chung, Sun Kyung Lee
Clin Exp Pediatr. 1992;35(10):1377-1388.   Published online October 15, 1992
The authors studied 24 cases of malignant neuronal tumors, 14 neuroblastomas and 10 ganglioneuroblastomas, immunohistochemically, using antibodies to neuroendocrine markers including neuron specific enolase (NSE), somatostatin, chromogranin, β-endorphin, and adrenocorticotrophic hormone (ACTH). The tissue specimens were obtained by biopsy or autopsy at Pusan National University Hopital and Pusan Paik Hospital from 1980 to 1989. The positive reactivity of markers in...
Dimension of Normal Coronary Arteries Determined by Cross-Sectional Echocardiograph
Jung Yun Choi, Yong Soo Yun, Chung Il Noh, Jong Un Choi, I Seok Kang
Clin Exp Pediatr. 1992;35(10):1336-1342.   Published online October 15, 1992
In order to determine the normal values of coronary arterial dimensions in children, eighty eight children without any cardiovascular diseases were studied with cross-sectional echocardiography. Age ranged from 1 day to 15 years. Four sites (proximal right coronary artery, left main, left anterior descending, and left circumflex coronary artery) were selected to measure the dimensions. The right coronary artery was measured...
Standard of Ear Size in Korean Children
Heon Seok Han, Hyung Ro Moon
Clin Exp Pediatr. 1992;35(8):1089-1095.   Published online August 15, 1992
Measurement of 1298 Korean Children in Seoul (male 661; female 637) resulted in normal standard data for ear length and width by their age and sex. 1) Ear length and width were as follows respectively : 36.0¡¾2.5mm 21.5¡¾2.5mm in male neonate, 56.3¡¾3.1mm 30.6¡¾3.2mm at 6yr boy, 63.2¡¾3.5mm 33.4¡¾3.2mm in 14 yr adolescent male, 35.5¡¾2.0mm 21.2¡¾2.1mm in female neonate, 54.6¡¾3.1mm 28.7¡¾2.4mm in...
A Clinical Study of Mycoplasma Pneumonia in Children During Recent 5 Years
In Seung Park, Ha Baik Lee
Clin Exp Pediatr. 1992;35(8):1082-1088.   Published online August 15, 1992
Mycoplasma pneumoniae infections are among the most frequent respiratory diseases of school-aged children, adolescents and young adults. However in preschool children a persistent nonproductive cough, fever and interstitial or lobular infiltrates on the chest radiograph can recently be recognized as presenting features of M. pneumoniae. We studied to find out the recent trends in epidermiologic and clinical variabilities of M. pneumoniae...
A Clinical and Statistical Analysis on Acute Appendicitis in Children
Eui Tak Oh, Kang Youl Bae, Sang Bong Lee, Hong Ja Kang, Hyung Kuk Kim, Woo Sik Chung, Kil Seo Kim
Clin Exp Pediatr. 1992;35(8):1073-1081.   Published online August 15, 1992
Thjis report is a clinical analysis of 367 cases of acute appendicitis in children under the age of 15, which were treated at Dae Dong Hospital during the past 5 year period from January 1986 to December 1990. The results were summerized as follows: 1) The incidence was low (0.5%) under the age of 3. 2) The sex ratio of male to female...
Acquired Renal Cystic Disease in Childhood Chronic Renal Failure
Tae Sun Ha, Seong Hoon Ha, Il Soo Ha, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Woo Sun Kim, Kim In One
Clin Exp Pediatr. 1992;35(8):1044-1050.   Published online August 15, 1992
The authors evaluated 19 childrenwith chronic renal failure patients diagnosed and followed up at the Department of Pediatrics, Seoul National University Hospital for the detection of acquired renal cystic disease (ARCD) with two radiologists by the means of ultrasonography. The results were as follows: 1) Of the 19 patients, male to femals ratio was 14:5 and of them, hemodialysis and peritoneal dialysis...
Permanent Epicardial Pacing in Pediatric Patients
I Seok Kang, Chung Il Noh, Jung Yun Choi, Yong Soo Yun
Clin Exp Pediatr. 1992;35(7):933-941.   Published online July 15, 1992
From September 1982 to July 1991, 40 infants and children aged 3 days to 13 years(mean 3.1 years) underwent implantation of 45 cardiac pacemakers using epicardial leads(40 primary implants, 5 re-implants). Nineteen patients required pacing for surgically acquired heart block, 1 for surgically acquired sinus node dysfunction, 11 for congenital complete atrio-ventricular(AV) block, 7 for nonsurgical sinus node dysfunction, and...
The Perceptions and Attitudes of Parents and Medical Personnel Toward Fever of Children
Hyo Nam Cho, Jung-Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1992;35(6):776-787.   Published online June 15, 1992
Children commonly complain of suffering fever ; however, as studies have demonstrated, parents of a febrile infant or young child are inclined to become overly concerned. The pupose of this study was to investigate the perceptions and attitudes of medical personnel as well as parents. The parents of 189 children and 150 medical personnel (47 nurse-aides, 56 nurses, and 47 doctors)...
Effucact of Adenosine Triphosphate in Infants and Children with Supraventricular Tachycardia
Yae Kyung Suh, Chung Il Noh
Clin Exp Pediatr. 1992;35(3):355-363.   Published online March 15, 1992
Acute tachyarrhythmia in infancy and childhood may be life-threatening if it is not treated promptly and accurately. The selection of a safe and effective pharmacologic agent is work in hand. We tried ATP (adenosine triphosphate) to pediatric patients with acute epidsodes of supraventricular tachycardia for therapeutic or diagnostic purpose and determined the safety and effectiveness of the drug. ATP was given...
The Pharmacokinetics and Biological Effects of Yeat Dervied Recombinant Methionyl Growth Hormone in growth Hormone Deficient Children
Byung Churl Lee
Clin Exp Pediatr. 1992;35(3):349-354.   Published online March 15, 1992
The parmacokinetics and biological effects of an recombinant methionyl growth hormone(LBD-003) produced by the expression of genomic hGH in a yeast cell line, were studied in growth hormone deficient children. Twelve patients were randomly assigned to two age-matched subcutaneous and intramuscular groups. Each group consists of 6 patients. Each subject received an dosage of 0.1 U hGH(LBD-003)/kg, BW, Blood was drawn before...
A clinical study of Graves' disease in children.
Kee Young Park, Ho Kyung Choi, Jong Jin Seo, Young Hun Chung
Clin Exp Pediatr. 1991;34(6):812-819.   Published online June 30, 1991
The authors analyzed the clinical manifestations, laboratory results, and relationship between the presence of antithyroid autoantibodies and response of short-term antithyroid medication in 20 children with Graves* disease who were diagosed at the Department of Pediatarics, Chungnam National Universtiy Hospital from March 1985 to February 1990. The results were as follows; 1) The ratio of male to female was 1:9. 2) The age distribution of patients ranged from...
Clinical review of abdominal masses in infants and children.
Dong A Lee, Woo Ryoung Lee, Jae Ock Park, Chang Hwi Kim, Sang Jhoo Lee
Clin Exp Pediatr. 1991;34(3):380-387.   Published online March 31, 1991
We reviewed 34 patients with palpable abdominal mass among 5,920 infants and children who admitted to the department of pediatrics of Soon Chun Hyang University from Jun. 1, 1986 to Aug. 31，1989. The results were as follows: 1) The incidence was 0.57% and the male: female ratio was 1:1.3. The mass was noted before 1 year of age in 23.5% of cases and under 5 years...
A clinical study of continuous ambulatory peritoneal dialysis in childhood.
Tae Sun Ha, Hye Won Park, Ja Wook Koo, In Seok Lim, Hae Il Cheong, Yong Choi, Kwang Wook Ko
Clin Exp Pediatr. 1991;34(3):363-370.   Published online March 31, 1991
A retrospective analysis of clinical with findings in 24 children continuous ambulatory peritoneal dialysis (CAPD) who were admitted to the Department of Pediatrics, Seoul National University Children’s Hospital from March, 1987 till August, 1990 was performed and the results were as follows; 1) The male to female ratio was 16:8, and the age distribution at the beginning of CAPD was from 59 days to 16.5...
Clinical studies of meningitis cases in children.
Chun Oh Lee, Song Nyeon Choi, Yong Wook Kim, Ki Bok Kim
Clin Exp Pediatr. 1991;34(2):206-216.   Published online February 28, 1991
A clinical studies were carried out on 442 cases who were admitted to the Department of Pediatrics, Kwangju Christian Hospital under impression of meningitis during a 7 year period form January, 1982 to December, 1989. The results are summerized; 1) No yearly fluctuation in incidence for both purulent and aseptic meningitis was noted, but decreasing tendency was clearly seen for tuberculous meningitis. 2) Purulent meningitis affected mostly babies...
Causes of Chronic Headache in Children.
Han Koo Moon, Son Moon Shin, Yong Hoon Park
Clin Exp Pediatr. 1990;33(12):1680-1688.   Published online December 31, 1990
Chonic headache is one of the most common symptoms in childhood diseases. Headache may occur as a symptom of many clinical disorders, including emotional disorders, head injuries, migraine, intracranial masses, intracranial inflammations or diseases of the eyes? ears, or nose, etc. But it may not always be possible to determine the cause in a given case despite elavorate diagnostic procedure because of non-obvious experession...
Blood Pressure Values of Primary, Middle and High School Children in Kwangju.
Jin Soo Choi, Ki Weon Park, Jae Sook Ma, Tai Ju Hwang
Clin Exp Pediatr. 1990;33(7):952-958.   Published online July 31, 1990
For the purpose of establishing normal reference values, the author measured blood pressure of 6, 221 school children (male 3,587, female 2,634) in Kwangju area using automatic noninvasive oscil- lometic method. Blood pressure increased as age and height increased. Distributions of systolic blood pressures were 101±7 mmHg (Mean±SD) in boys and 102±7mmHg (Mean±SD) in sgirls at age 7 and increased with a rate of 1,6...