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Original Article
Random Urine Ca/Cr Ratio in Healthy Neonates
Hea Young Lee, So Young Park, Eun Sun Yoo, Eun Ae Park, Seung Joo Lee
Clin Exp Pediatr. 1998;41(3):378-382.   Published online March 15, 1998
Purpose : Recently, in high risk preterm infants, we experienced high incidence of hypercalciuria, nephrolithiasis & nephrocalcinosis. To screen hypercalciuria, we need the normal value of random urine Ca/Cr ratio in healthy neonates according to gestational age, postnatal age, milk and calcium intake. Methods : Random urine Ca/Cr ratio was checked in 260 healthy full-term infants at the 2-7th day, and...
Clinical Study and Diagnostic Value of the Lung Perfusion Scan in Foreign Body Aspiration
Gyo-Dang Koo, Young-Ho Rah, Chong-Woo Bae, Sa-Jun Chung, Yong-Mook Choi
Clin Exp Pediatr. 1998;41(1):74-80.   Published online January 15, 1998
Purpose : Early diagnosis of foreign body aspiration and removal of the inhaled material may save the patient from chronic illness and may prevent serious complications. At present the diagnostic problems of bronchial foreign bodies are being solved by using the lung scanning technique. Therefore, we investigated the clinical study and diagnositic value of the lung perfusion scan in foreign body aspiration. Methods : Eighteen...
Interim Results of Single Stage Operation for Coarctation of Aorta with Large Ventricular Septal Defect in Infancy
Ho Sung Kim, Chung Il Noh, Yong Soo Yun, Jung Yun Choi, Jeong Ryul Lee, Yong Jin Kim, Joon Ryang Roh
Clin Exp Pediatr. 1997;40(9):1250-1257.   Published online September 15, 1997
Purpose : There are controversies in the operative methods of aorta with ventricular septal defect in infancy. Recent results of single stage operation for coarctation of aorta with intracardiac defects were regarded as comparable to staged operation. We evaluated our interim results after single stage operation for coarctation of aorta with large ventricular septal defect in infancy. Methods : Twenty six infants who had received...
Case Report
A Case of Neuronal Heterotopia
Jeong Hae Joo, Eun Joo Seok, Min Jeong Kim, Son Sang Seo
Clin Exp Pediatr. 1997;40(8):1173-1177.   Published online August 15, 1997
Neuronal migrational disorders of the brain represent abnormalities in the formation of the neocortex caused by faulty migration of the subependymal neuroblasts. The neuroblasts normally migrate between the sixth and 15th gestational week and in doing so form the six-layered neocortex. When the migration does not occur in a normal fashion the resultant brain anomalies include lissencephaly, pachygyria, schizencephaly, hemimegalencephaly, heterotopia, and polymicrogyria. Neuronal heterotopia is...
Original Article
The Clinical Study on Conversion Rate of Mantoux Test, Change of Local Lesion and Complication after Multipuncture BCG Vaccination in Neonates
Myung Ho Oh, Kee Hyuck Kim, Jae Gun Sim
Clin Exp Pediatr. 1997;40(8):1120-1130.   Published online August 15, 1997
Purpose : Ugly ulcer and keloid formation of injection site has sometimes been a problem in Korea from the cosmetic point of view in intradermal vaccination. Since 3 or 4 years ago, multipuncture BCG vaccination has been used in Korea, there are no data and information about multipuncture BCG vaccination. We therefore performed this study to evaluate of conversion rate, complication and to make...
Zinc and Copper Concentrations and Their Correlation with Protien in Cerebrospinal Fluid of Children with Neurologic Disorders
Myung Joon Cha, Young Joon Kim, Ha Joo Choi, Woo Kap Chung
Clin Exp Pediatr. 1997;40(8):1062-1070.   Published online August 15, 1997
Purpose : The importance of trace elements in their effect on the physiology and pathology of the central nervous system is well recognized. Changes in the concentrations of these elements in the brain could take place in pathological states. Recently, a greater emphasis has been given to the role of trace elements in the function of the nervous system both in normal and pathological...
Case Report
A Case of Severe Pulmonary Complication and ARDS Secondary to Peanut Aspiration in 15 Month Old Male
Sung Keun Moon, Chang Keun Kim, Churl Young Chung
Clin Exp Pediatr. 1997;40(3):423-428.   Published online March 15, 1997
Foreign body aspiration(especially peanut) is the leading cause of accidental death in children under 1 year of age and most cases of serious aspiration occur between the age of 1 and 3. We report a case of severe pulmonary complication and adult respiratory distress syndrome(ARDS) secondary to peanut aspiration in 15 month old male in spite of all removal(9 pieces) by ventilating bronchoscope. Chest...
Original Article
The Study of Serum Aminotransferase and AST/ALT Ratio in Pediatric Patients with Acute Hepatitis
Soo Mi Jung, Chang Rang Kang, Man Taeg Oh, Jong Duck Kim
Clin Exp Pediatr. 1996;39(10):1364-1370.   Published online October 15, 1996
Purpose : Serum level of the aminotransferase is the most common test in use to assess hepatocellular injury and are sensitive test of hepatocyte necrosis, but both AST and ALT level in serum rise in a variety of hepatic disorders. Some clinical study reports that AST/ALT ratio was possible to predict prognostic outcome of infants with liver disease. We have tried to assess whether...
Arterial Oxygen Desaturation after Salbutamol Nebulization in Wheezy Infants and Children
Eun Sun Yoo, Jung Won Seo, Seung Joo Lee
Clin Exp Pediatr. 1996;39(7):953-961.   Published online July 15, 1996
Purpose : Nebulized selective β2-adrenoreceptor agonists have been widely used in acute asthma and selectively in acute bronchiolitis. However, nebulized salbutamol have been reported to cause arterial oxygen desaturation in some of the acute bronchiolitis and severe asthma patients. This may be the results of a paradoxical bronchoconstriction linked to acidic and hyper-osmolar nebulized salbutamol solution and etc. We assessed the changes in arterial...
Ischemic Hepatitis in Children after Cardiac Operation -Analysis of Clinical Characteristics, Risk Factors and Outcome-
Kyung Mo Kim, Jeong Kee Seo
Clin Exp Pediatr. 1995;38(11):1540-1546.   Published online November 15, 1995
Purpose : We have experienced frequently the ischemic hepatitis after cardiac operations which shows rapid striking rise of transaminase. But the ischemic hepatitis in children after cardiac operation is not defined yet in Korea. We examined the clinical characteristics and analyzed the risk factors and outcome in 20 children who showed typical clinical course of ischemic hepatitis after cardiac operation. Methods...
Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction
Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong
Clin Exp Pediatr. 1995;38(8):1077-1086.   Published online August 15, 1995
Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures...
Case Report
Three Cases of Pneumoperitoneum in Ventilated Newborns
Chun Ok Yang, Ho Young Lee, Won Kju Choe, Baek Keun Lim, Jong Soo Kim
Clin Exp Pediatr. 1995;38(7):1006-1011.   Published online July 15, 1995
Pneumoperitoneum in the newborn is usually a surgical emergency resulting from gastroint-estinal perforation. However, pneumoperitoneum can occur secondary to a pulmonary air leak which progresses from the mediastinum to the retroperitoneum by way of perivascular spaces and then to the peritoneum following rupture. We have observed this phenomenon in three ventilated newborn. A brief review of the related literatures was...
Erratum
Three Cases of Necrotizing Lymphadenitis in Childhood
Seong Hoon Hah, Dong Woon Shin, Kyung Hee Lee, Tae Sun Ha, Beom Soo Park, Heon Seok Han, Sang-Hoon Cha, Geon Kook Lee
Accepted January 1, 1970  
Necrotizing lymphadenitis(named as "Kikuchi disease"), initially described by a Japanese pathologist as "a histiocytic necrotizing lymphadenitis with paracortical necrosis, plasmacytoid monocytes infiltration and prominent phagocytic appearance" has been found worldwide. Be-cause of its self-limited course, it has been well known that what should be considered as more important issues are its deatiled pathologic criteria for confirmation and thorough concern about...
Original Article
Relationship of Echocardiographic, Shunt Flow, and Angiographic Size to the Operation Diameter of the Atrial Septal Defect
Dae Kwon Hong, Hae Yong Lee, Baek Keun Lim
Clin Exp Pediatr. 1995;38(2):232-239.   Published online February 15, 1995
This report is based on analysis of admissions to the department of pediatric at the Wonju Christian Hospital during the 3 3/4-year period from January 1989 to September 1993 with an Isolated ostium secundum ASD. Several methods of assessment of ASD size, namely, echographic, pulmonary-to-systemic flow ratio(Qp:Qs), and angiographic measures, were undertaken in a group of 37 patients, who were being...
Case Report
A Case of Congenital Agammaglobulinemia
Sang Yong Kim, Jong Hyun Kim, Jin Han Kang, Joon Sung Lee, Sang In Shim
Clin Exp Pediatr. 1995;38(1):99-103.   Published online January 15, 1995
Congenital agammaglobulinemia was described first among all human immunodeficiencies, and characterized by defect of B lymphocyte maturation and severe panhypogammaglobulinemia. These patients frequently acquire infections with high-grade extracellular pyogenic pyogenic organisms since infancy. We experienced a case of congenital agammaglobulinemia in a 10 years old male. He had history of recurrent pneumonia and purulent otitis media since late infancy. Also he...
Original Article
Clinical Study of Foreign Body Aspiration in Infants and Children
Dong Kyun Ryu, Su Jin Park, Kang Seo Park, Wan Seob Kim
Clin Exp Pediatr. 1995;38(1):66-74.   Published online January 15, 1995
A clinical study was done on 42 cases of inpatients, who had been admitted for foreign body aspiration form January 1979 to June 1992. We obtained the following results by analysing the records of their treatment during that time. 1) 31(73.8%) of these cases were below the age of 3 years. 25(59.4%) were below the age of 2. The ratio of male...
The Variations of CSF Glucose-To-Blood Glucose Ratio according to the Time of Blood Sampling in Asepetic Meningitis
Dong Gui Jang, Yong Seok Choi, Mee Kyoung Lee, Chang Hee Kim, Dong Jin Lee
Clin Exp Pediatr. 1994;37(12):1687-1692.   Published online December 15, 1994
The Measurement of CSF glucose and CSF glucose-to-blood glucose ratio is a very useful laboratory test for the differential diagnosis of meningitis. We have observed the change of blood glucose & CSF glucose-to-blood glucose ratio according to the time of blood sampling in 84 patients with aseptic meningitis who had been admitted to the department of peditrics, Dong Kang hospital...
Diagnosis of Thoracic Lesions in Children by Fine Needle Aspiration Biopsy
Dong Nam Kim, Nam Su Kim, Hahng Lee, Jong Sung Kim, Suk Chul Jeon
Clin Exp Pediatr. 1994;37(11):1559-1564.   Published online November 15, 1994
To elucidate the clinical availability of FNAB, we reviewed retrospectively medical records of 30 patients who had infiltrative pulmonary lesion or pulmonary nodule of mediastinal mass, and got percutaneous fine needle aspiration biopsy using Wescott needle, 20~22 gauge, at the department of Pediatrics, Hanyang university hospital from July, 1986 to June, 1993. The obtained results were as follow: 1) There were 30...
Antilymphocyte Globulin Therapy for Aplastic Anemia in Children
Soo Jong Hong, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1994;37(11):1526-1539.   Published online November 15, 1994
Immunosuppressive therapy based on the use of antilymphocyte globulin (ALG) has become standard therapy for patients with aplastic anemia who are not eligible for bone marrow transplantation. In this study, T cell subsets before and after ALG therapy, hematologic responses, complications and prognostic factors were analysed. Eleven (42%) out of twenty-six patients treated with ALG showed response, but...
Studies on the B Cell Proliferation and Differentiation Factors in Human B Cell System
Kwang-Ju Lee, Young-Hun Chung, Jae-Ho Lee
Clin Exp Pediatr. 1994;37(10):1386-1396.   Published online October 15, 1994
We have studied the function of lymphokines on human tonsillar B cell proliferation and differentiation. B cells were stimulated with Staphylococcus aureus Cowan1(SAC) or anti-μ bead. The followings showed the results of this study. 1) In B cell activation, SAC induced B cell DNA synthesis but anti-μ bead did not. SAC could activate and proliferate B cells. Minimal number of B cells...
Case Report
Transient Methemoglobinemia with Acidosis in Newborn
Heng Mi Kim
Clin Exp Pediatr. 1994;37(3):416-421.   Published online March 15, 1994
methemoglobinemia is an uncommon clinicl problem generally caused by inherited disorders of hemoglobin metabolism or environmental toxicity from oxidizing agents. Since methemoglobin has no oxigen carrying capacity, patient with severe methemoglobinemia may have dangerous hypoxia even when arterial oxygen tension is normal. Degree of exposure to oxidants which are benign for older individuals may produce severe methemoglobinemia in newborns. Acidosis without...
Original Article
Clinical Observation of Meconium Aspiration Syndrome : In Relation to Fetal Heart Rate Monitoring
Young Ran Yoon, Jin Sook Kim, Mi Kyung Kim, Sun Young Kho, Seong Ja Lee, Mi Jung Kim, Hye Kyung Han, Kyung Hoon Choi, Mi Na Lee
Clin Exp Pediatr. 1993;36(12):1656-1662.   Published online December 15, 1993
To identify the neonates at the risk of having meconium aspiration syndrome, the perinatal characteristics and finding of fetal heart rate monitorings in 366 neonates who had meconium-stained amniotic fluid were retrospectively reviewed. The results were as follows ; 1) Overall incidence of MAS was 0.7%. 2) Mortality rate of MAS was 5.8%. 3) The mean Apgar scores at 1-and 5-minute were...
Serum Alkaline Phosphatase Activity after Intravenous Administration of Albumin Preparation
June Huh, Kang Mo Ahn, Ja Wook Koo, Il Soo Ha, Hae Il Cheong, Yong Choi
Clin Exp Pediatr. 1993;36(6):830-836.   Published online June 15, 1993
Serum alkaline phosphatase(AP) activity is elevated in hepatobiliary disease, bone disease, pregnancy and certain neoplasms. Recently we experienced marked elevation of serum AP activity after administration of ablumin preparation in nephrotic patients who suffered from hypovolemic symptoms. So serum AP activity and the isoenzymes in the albumin preparations & patient뭩 serum after the administration of albumin preparation were studied. Serum...
The Factors on the Development of Coronary Arterial Involvement in Kawasaki Disease
Sang Yen Kim, Jong Hyun Kim, Jong In Byun, Won Bae Lee, Byung Churl Lee, Kyung Tai Whang, Kyong Su Lee, Sung Hoon Cho
Clin Exp Pediatr. 1992;35(10):1328-1335.   Published online October 15, 1992
In Kawasaki disease, coronary arterial involvement is an important prognostic factor. Many studies have reported about risk factors of coronary artery disease in Kawasaki disease. This study was designed to evaluate factors influencing coronary arterial involvement and to evaluate the effect of intravenous gammaglobulin (IVG) when admitted on the widely used criteria in Korea. Fiftyfour patients meeting the CDC criteria...
Short-Term Results of Arterial Switch Operation for Transposition of Great Arteries
Yong Soo Yun, Yong Won Park, Chul Il Noh, Jung Yun Choi, Yong Jin Kim, Joon Ryang Rho, Kyung Pil Suh
Clin Exp Pediatr. 1992;35(6):795-803.   Published online June 15, 1992
The operative results of 50 cases who underwent arterial switch operation from January, 1986 to March, 1991 were evaluated. The results were summarized as follows ; 1) Three main combined cardiac defects of ASO cases were PDA(60%), VSD(56%) and ASD(46%), and most common type of VSD was perimembranous(64.3%) and most frequent pattern of coronary artery was usual pattern of TGA (84%). 2)...
Clinical Observation of Meconium Aspiration Syndrome: Prognostic Implication of Early Meconium Suctioning
Dae Hyun Kim, Dong Hoon Ko, Young Jong Woo, Young Youn Choi, Tae Ju Hwang
Clin Exp Pediatr. 1992;35(4):484-491.   Published online April 15, 1992
The authors observed the clinical findings of 36 patients with meconium aspiration syndrome(MAS) to evaluate the effect of early appropriated meconium suctioning on the morbidity and mortality of the syndrome. Patients in the study group, 20 babies born in Chonnam university Hospital, received appropriate meconium suction through endotracheal tube during and rig-ht after the delivery, while the patients in the...
Clinical Study of Gastrointestinal Perforation in the Newborn
K.N. Kim, Y.T. Jang, O.K. Lee, W.S. Kim
Clin Exp Pediatr. 1992;35(4):476-483.   Published online April 15, 1992
A clinical study was made on 17 neonates with gastrointestinal perforation admitted to the department of pediatrics Presbyterian Medical Center from January 1980 to January 1991. The following results were obtained. 1) Males were predominantly developed and the time of perforations occurs mainly in the 1 st week of life(70.6%). 2) The 17.5 percent of total cases were prematurity of low birth infant. 3)...
Congenital cystic diseases of the lung.
Won Soon Park, Young Pyo Chang, Hee Ju Kim, Young Yull Koh, Jung Hwan Choi, Chong Ku Yun, Joo Hyun Kim
Clin Exp Pediatr. 1991;34(12):1671-1677.   Published online December 31, 1991
Congenital cystic diseases of the lung (CCDL) is a clinical group of disorders characterized by a cystic appearance of pulmonary tissue. It can be classified into four distinct categories: 1) Congenital lobar emphysema (CLE), 2) Congenital cystic adenomatoid malformation (CCAM), 3) Pulmonary sequeestration (PS), and ^Bronchogenic cyst (BC). 24 patients with CCDL admitted to the Seoul National University Children’s Hospital from January 1984 to June...
Physical Growth According to Sexual Maturation of Korean Adolescents
Hwan Gyu Park, Chang Ho Hong, Duk Hi Kim
Clin Exp Pediatr. 1994;37(9):1187-1195.   Published online September 15, 1991
Adolescence is the period in which physical, mental and social maturation occurs and it is an important transit stage, changing from childhood to adulthood. This is a period in which important changes occur physically such as rapid growth in height and weight gain but significant differences in growth may occur for the same age. Therfore, the degree of sexual maturation...
A clinical study on meconium-stained babies.
Cheol Ki Min, Sung Suk Bang, Chong Young Park, Hae Ran Lee, Choon Myung Ro
Clin Exp Pediatr. 1991;34(1):24-30.   Published online January 31, 1991
Among a total of 667 newborns delivered at Han Gang Sacred Heart Hospital from January 1988 to July 1989, a clinical study was done regarding meconium-stained babies. The results were summarized as follows: 1) The incidence of meconium staining was 25.9% (173 babies) and there was no difference of frequency in sex. 2) The higher the birth weigt and the gestational age, the higher the incidence of...