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Original Article
The immunogenicity and safety of three-component DTaP vaccine in Korean infants
Jin Han Kang, Jong Hyun Kim, Jung Hyun Lee, Soo Young Lee, Young Jin Hong, Chang Hwi Kim
Clin Exp Pediatr. 2007;50(4):355-362.   Published online April 15, 2007
Purpose : We conducted the study to evaluate the immunogenicity and safety of three component DTaP vaccine (Infanrix ) in a group of Korean healthy infants on a three-dose primary vaccination. And we compared the immunogenicity of this DTaP vaccine with two component DTaP vaccine which has been widely used in Korea. Methods : We enrolled one hundred fifty one healthy...
Pertussis Antibodies in the Sera of Children after Acellular Pertussis Vaccination
Jeong Hwa Lee, Young Hee Ha, Ji Whan Han, Won Bae Lee, Kyong Su Lee
Clin Exp Pediatr. 1997;40(2):167-172.   Published online February 15, 1997
Purpose : The pertussis vaccines are divided into whole-cell vaccine and acellular vaccine. Purified component acellular pertussis vaccine, originally developed in Japan, has been used for primary immunization series in Korea since 1984. We performed this study to evaluate the prevalence of pertussis antibodies following vaccination with acellular pertussis vaccine. Methods : We randomized 80 children who were immunized according to vaccine schedules...
The effect of pertussis vaccine on streptozotocin induced diabetic rats.
Kyung Rae Moon, Kwang Rhun Koo, Sang Kee Park, Yeong Bong Park, Byoung Rai Lee, Keun Hong Kee
Clin Exp Pediatr. 1991;34(7):897-906.   Published online July 31, 1991
Streptozotocin produces diabetes in laboratory animals through the destuction of the pancreatic beta cells. The diabetogenic activity of STZ, however, is known to be modified by several agents such as nicotinamide, diazoxide, adrenergic blockers and petussis vaccine (PV). The present study was undertaken to observe the protective effect of PV or boiled pertussis vaccine (bPV; incubating the PV at 80 C for 30 mintues)...
The Effect of Pertussive Vaccine & Cyclosporin on Streptozotocin Induced Diabetic Rats.
Duk Hi Kim
Clin Exp Pediatr. 1988;31(7):914-923.   Published online July 31, 1988
The injection of streptozotocin (STZ) at higher dose (60 mg/kg) to young male rats produce direct beta cell destruction and lead to insulin dependent diabetes (IDD). In contrast, the injection of multiple smaller dose of STZ (40 mg/kg/d for 5 days) produce IDD, which resembles type 1 diabetes in man. The protective effect of pertussis vaccine (PV) & cyclosporin (CA) against the develoment...
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