Aeroallergens are important causative factors of allergic diseases. Previous studies on aeroallergen sensitization rates investigated patients groups that had visited pediatric allergy clinics. In contrast, we investigated sensitization rates in a general population group of elementary school to teenage students in Incheon, Jeju, and Ulsan.

After obtaining parental consent, skin-prick tests were performed on 5,094 students between March and June 2010....

Fractional exhaled nitric oxide (FeNO) and forced expiratory flow between 25% and 75% of vital capacity (FEF_25-75) are not included in routine monitoring of asthma control. We observed changes in FeNO level and FEF_25-75 after FeNO-based treatment with inhaled corticosteroid (ICS) in children with controlled asthma (CA).

We recruited 148 children with asthma (age, 8 to 16 years) who had maintained...

Leptin has been considered a link between metabolic state and reproductive activity. Defective reproductive function can occur in leptin-deficient and leptin-excessive conditions. The aim of this study was to examine the effects of centrally injected leptin on the hypothalamic KiSS-1 system in relation to gonadotropin-releasing hormone (GnRH) action in the initial stage of puberty.

Leptin (1 µg) was injected directly into...

Short sleep duration is associated with obesity. Urinary 6-sulfatoxymelatonin (6-OHMS), the principal metabolite of melatonin, is closely related with sleep. We evaluated the difference in urinary 6-OHMS levels between obese girls and normal weight girls, and the relationship of urinary 6-OHMS with other hormones regulating body weight and metabolism.

A total of 79 girls (6.3 to 12.4 years) were included in...