- Review Article
- Gastroenterology
- Nutritional concerns in pediatric inflammatory bowel disease
- Yong Joo Kim
- Clin Exp Pediatr. 2016;59(6):247-251. Published online June 30, 2016
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The pathophysiology and fundamental etiologic mechanism of inflammatory bowel disease (IBD) is not well understood even though therapeutic regimens and drugs are rapidly evolutionary. IBD has complicated connections with genetic, immunologic, gut microbial, environmental, and nutritional factors. It is not clearly well known to the physicians how to feed, what nutrients are more helpful, and what food to be avoided....
- Original Articles
- Infection
Pneumocystis jirovecii pneumonia in pediatric patients: an analysis of 15 confirmed consecutive cases during 14 years- Kyung-Ran Kim, Jong Min Kim, Ji-Man Kang, Yae-Jean Kim
- Clin Exp Pediatr. 2016;59(6):252-255. Published online June 30, 2016
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Purpose Pneumocystis jirovecii pneumonia occurs in various immunocompromised patients. Despite the prophylaxis strategies in clinical practice, certain patients developP. jirovecii pneumonia. This study was performed to investigate pediatric cases withP. jirovecii pneumonia in a single center.Methods We identified pediatric patients younger than 19 years with microbiologically confirmed
P. jirovecii pneumonia from January 2000 to February 2014. A retrospective chart review...
- Usefulness of interferon-γ release assay for the diagnosis of latent tuberculosis infection in young children
- Ki Wook Yun, Young Kwang Kim, Hae Ryun Kim, Mi Kyung Lee, In Seok Lim
- Clin Exp Pediatr. 2016;59(6):256-261. Published online June 30, 2016
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Purpose Latent tuberculosis infection (LTBI) in young children may progress to severe active tuberculosis (TB) disease and serve as a reservoir for future transmission of TB disease. There are limited data on interferon-γ release assay (IGRA) performance in young children, which our research aims to address by investigating the usefulness of IGRA for the diagnosis of LTBI.
Methods We performed a tuberculin skin...
- Cardiology
- The effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline-induced right ventricular failure
- Hyun Kyung Bae, Hyeryon Lee, Kwan Chang Kim, Young Mi Hong
- Clin Exp Pediatr. 2016;59(6):262-270. Published online June 30, 2016
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Purpose Pulmonary arterial hypertension (PAH) leads to right ventricular failure (RVF) as well as an increase in pulmonary vascular resistance. Our purpose was to study the effect of sildenafil on right ventricular remodeling in a rat model of monocrotaline (MCT)-induced RVF.
Methods The rats were distributed randomly into 3 groups. The control (C) group, the monocrotaline (M) group (MCT 60 mg/kg) and the...
- Neurology
- Clinical importance of F-waves as a prognostic factor in Guillain-Barré syndrome in children
- Eung-Bin Lee, Yun Young Lee, Jae Min Lee, Su Min Son, Su-Kyeong Hwang, Soonhak Kwon, Sae Yoon Kim
- Clin Exp Pediatr. 2016;59(6):271-275. Published online June 30, 2016
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Purpose A limited number of studies have examined the link between F-wave abnormalities and clinical presentation in pediatric Guillain-Barré syndrome (GBS). Therefore, this study examined the importance of F-wave abnormalities as a prognostic factor in pediatric GBS patients.
Methods The records and electrodiagnostic studies (EDS) of 70 GBS patients were retrospectively evaluated, and divided into 2 groups according to the results of EDS....
- Case Reports
- Genetics and Metabolism
- A rare case of Sjogren-Larsson syndrome with recurrent pneumonia and asthma
- Azita Tavasoli, Shirin Sayyahfar, Babak Behnam
- Clin Exp Pediatr. 2016;59(6):276-279. Published online June 30, 2016
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Sjogren-Larsson syndrome (SLS) is a rare autosomal recessive neurocutaneous disorder with worldwide incidence of 0.4 per 100,000 people. It is characterized by the triad of congenital ichthyosis, spastic diplegia or quadriplegia, and mental retardation. Herein we report a 2-year-old male child with SLS, asthma, and recurrent pneumonia. SLS was confirmed by a molecular genetics study that revealed a deletion mutation...
- Neurology
- Two cases of familial cerebral cavernous malformation caused by mutations in the
CCM1 gene - Im-Yong Yang, Mi-Sun Yum, Eun-Hee Kim, Hae-Won Choi, Han-Wook Yoo, Tae-Sung Ko
- Clin Exp Pediatr. 2016;59(6):280-284. Published online June 30, 2016
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Cerebral cavernous malformation (CCM) is a vascular malformation characterized by abnormally enlarged capillary cavities without any intervening neural tissue. We report 2 cases of familial CCMs diagnosed with the
CCM1 mutation by using a genetic assay. A 5-year-old boy presented with headache, vomiting, and seizure-like movements. Brain magnetic resonance imaging (MRI) revealed multiple CCM lesions in the cerebral hemispheres. Subsequent...
