Clinical and Experimental Pediatrics

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Ki Young Kwon (Kwon KY)

1 Article

Original Article

Anticancer Effect of Arsenic Trioxide in Acute Promyelocytic Leukemia

Ki Young Song, Jin Hye Park, Yoon Jung Cho, Won Ki Baek, Ki Young Kwon, Heung Sik Kim, Chin Moo Kang

Clin Exp Pediatr. 2000;43(3):327-334. Published online March 15, 2000

Purpose : Acute promyelocytic leukemia(APL or AML, M3) represents an unique model for cancer research in terms of biological and clinical features. Since 1988, it has been widely confirmed that all-trans retinoic acid(ATRA) can induce complete clinical remission in over 85% of APL patients by a differentiation process, with PML-RARα protein possibly being the direct target of ATRA. However, ATRA...

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