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Purpose : Several cytokines play important roles in the inflammatory process of Henoch-Sch lein Purpura (HSP). It is likely that transforming growth factor-β (TGF-β) is involved in the pathogenesis of HSP. The purpose of this study is to investigate whether TGF-β promoter polymorphism is associated with the renal involvement of childhood HSP.
Methods : Thirty-four patients younger than 15 years, who... |