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Review Article

Infection

Four months of rifampicin monotherapy for latent tuberculosis infection in children

Chi Eun Oh, Dick Menzies

Clin Exp Pediatr. 2022;65(5):214-221. Published online October 29, 2021

Web of Science 6 Crossref 6

· Recently, the importance of a short-term treatment regimen including rifamycin has been highlighted in the treatment of latent tuberculosis infection (LTBI).
· Four prospective or retrospective studies in children consistently reported that a 4-month daily rifampicin regimen (4R) had a higher completion rate than and comparable safety to a nine-month daily isoniazid regimen.
· We suggest rifampicin 20–30 mg/kg/day for children aged 0–2 years and 15–20 mg/kg/day for children aged 2–10 years in 4R to treat LTBI.

DOI: https://doi.org/10.3345/cep.2021.01186

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