Clinical and Experimental Pediatrics

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Original Article

Effect of CpG Oligodeoxynucleotides on Airways of Mice with Established Airways Inflammation

Hei-Won Hwang, Su-Jin Kim, Won-Duk Kim, Sung-Min Cho, Dong-Suk Lee, Sung-Min Choi

Clin Exp Pediatr. 2002;45(7):875-883. Published online July 15, 2002

Purpose : Airways eosinophilia and increased IgE, characteristic features of asthma, result from a predominant Th2 response. In this study, we investigated the effect of CpG oligodeoxynucleotides (ODNs) on the inhibition of airways eosinophilia in mice with established airway inflammation. We also investigated the immunological mechanisms involved. Methods : Groups of BALB/c mice were sensitized intradermally with ovalbumin(OVA). At week 10,...

Case Report

A Case of Hypoglossia-Hypodactylia with t(3q;19p)

Hei-Won Hwang, Ji-Sun Mok, Ji-Eun Kim, Dong-Suk Lee, Doo-Kwun Kim, Sung-Min Choi, Woo-Taek Kim

Clin Exp Pediatr. 2001;44(11):1311-1315. Published online November 15, 2001

Hypoglossia-hypodactylia syndrome is a congenital disease which is characterized by severe micrognathia, hypoglossia and various anomalies of extremities. This was first reported as 'aglossia congenita' back in 1932 by Rosenthal, and has been reported many times ever since, but has never been reported in Korea. Hall first used the term 'hypoglossia-hypodactylia syndrome', and classified it as one of the oromandibular-limb...

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Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)