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Long-term recombinant interferon-γ treatment in 2 cases of osteopetrosis

Dong-Yun Kim, Dong-Kyun Han, Hee-Jo Baek, Sung-Taek Jung, Hoon Kook, Tai-Ju Hwang

Clin Exp Pediatr. 2007;50(11):1129-1133. Published online November 15, 2007

Osteopetrosis, a rare osteosclerotic bone disease characterized by a defect in osteoclast function and the reduced generation of superoxide by leukocytes, can be classified into several types based on their mode of inheritance, age of onset, severity, and associated clinical symptoms. Stem cell transplantation is the only curative therapy for the infantile malignant type, although alternative treatments, such as corticosteroids,...

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