Clinical and Experimental Pediatrics

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Original Article

Toll-like receptor 2 expression on monocytes from patients with BCG vaccine-associated suppurative lymphadenitis

Hyun Joo Oh, Kyung-Sue Shin

Clin Exp Pediatr. 2009;52(6):667-673. Published online June 15, 2009

Purpose : Toll-like receptor 2 (TLR2) is critical in the immune response to mycobacterial infections. The purpose of this study was to analyze TLR2 surface expressions and TLR2-mediated tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) production in patients with BCG vaccine-associated suppurative lymphadenitis. Methods : Peripheral monocytes were separated from 16 patients with BCG vaccine-associated suppurative lymphadenitis and 10 healthy...

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