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The Effect of Angiotensin Converting Enzyme Gene Polymorphism in Children with Henoch-Schonlein Purpura Nephritis

Chang Woo Ha, Ji Young Kim, Jeong Nyeo Lee, Jeong Hwa Lee, Woo Yeong Chung

Clin Exp Pediatr. 2002;45(7):884-890. Published online July 15, 2002

Purpose : Henoch-Schonlein purpura(HSP) nephritis has been reported to vary from 25 to 50% among HSP patients and is a common cause of chronic glomerulonephritis in children. In our study, we evaluated the distribution and the association of the Insertion/Deletion(I/D) polymorphism of angiotensin converting enzyme(ACE) gene with clinical manifestations, particularly proteinuria in children with HSP nephritis, compared with that in...

Pertussis Antibodies in the Sera of Children after Acellular Pertussis Vaccination

Jeong Hwa Lee, Young Hee Ha, Ji Whan Han, Won Bae Lee, Kyong Su Lee

Clin Exp Pediatr. 1997;40(2):167-172. Published online February 15, 1997

Purpose : The pertussis vaccines are divided into whole-cell vaccine and acellular vaccine. Purified component acellular pertussis vaccine, originally developed in Japan, has been used for primary immunization series in Korea since 1984. We performed this study to evaluate the prevalence of pertussis antibodies following vaccination with acellular pertussis vaccine. Methods : We randomized 80 children who were immunized according to vaccine schedules...

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