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Review Article

Cerebral organoid research for pediatric patients with neurological disorders

Jin Eun, Jung-Eun Lee, Seung-Ho Yang

Cerebral organoids derived from human induced pluripotent stem cells offer a groundbreaking foundation for the analysis of pediatric neurological diseases. Unlike organoids from other somatic systems, cerebral organoids present unique challenges, such as the high sensitivity of neuronal cells to environmental conditions and the complexity of replicating brain-specific architectures. Cerebral organoids replicate the human brain development and pathology, enabling research...

DOI: https://doi.org/10.3345/cep.2024.01235 [Accepted]

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