Clinical and Experimental Pediatrics

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Original Article

Immunogenicity of a Recombinant Hepatitis B Virus Vaccine Compared With a Plasma-derived Hepatitis B Vaccin~ and of Vaccination Schedules in Neonates

Ae Sil Kang, Jong Sin Kim, Jae Won Huh, Chang Youn Lee, Hyun Gi Jung, Jae Sun Park, Kwang Soo Hwang

Clin Exp Pediatr. 1995;38(11):1525-1534. Published online November 15, 1995

Purpose : Hepatitis B virus (HBV) vaccine was developed against HBV infection, and used widely in the world. The plasma-derived HBV vaccine was prepared from the plasma of chronic hepatitis B virus carrier. But, the plasma-derived HBV vaccine had many kinds of problems, such as the limitation of source, expensiveness, and the possibility of infection which spread through blood. To avoid these...

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