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Original Article
Occurrence and characterization of oseltamivir-resistant influenza virus in children between 2007-2008 and 2008-2009 seasons
Seoung Geun Kim, Yoon Ha Hwang, Yung Hae Shin, Sung Won Kim, Woo Sik Jung, Sung Mi Kim, Jae Min Oh, Na Young Lee, Mun Ju Kim, Kyung Soon Cho, Yeon Gyeong Park, Sang Kee Min, Chang Kyu Lee, Jun Sub Kim, Chun Kang, Joo Yeon Lee, Man Kyu Huh, Chang Hoon Kim
Clin Exp Pediatr. 2013;56(4):165-175.   Published online April 22, 2013
Purpose

There was a global increase in the prevalence of oseltamivir-resistant influenza viruses during the 2007-2008 influenza season. This study was conducted to investigate the occurrence and characteristics of oseltamivir-resistant influenza viruses during the 2007-2008 and 2008-2009 influenza seasons among patients who were treated with oseltamivir (group A) and those that did not receive oseltamivir (group B).

Methods

A prospective study was conducted...

Oseltamivir efficacy, side effects, and safety in children with influenza
Eun Sun Seo, Geun Hwa Park, Sung Won Kim, Sung Won Kim, Woo Sik Jung, Kyung Soon Cho, Yeon Gyeong Park, Chang Kyu Lee, Chun Kang, Joo Yeon Lee, Woo Young Choi
Clin Exp Pediatr. 2010;53(1):56-66.   Published online January 15, 2010
Purpose : Although oseltamivir is widely used for treatment of influenza, few clinical studies of its efficacy and resistance have been performed in Korea. We evaluated the safety, side effects, and efficacy of oseltamivir treatment in Korean pediatric patients. Methods : We analyzed 321 children diagnosed with influenza at Busan St. Mary's Medical Center, Korea, between January 2008 and June...
Clinical usefulness of rapid antigen test to detect respiratory syncytial virus infection
Hyung Su Kim, Hee La Kim, Ki Hyung Park, Kyung Soon Cho
Clin Exp Pediatr. 2008;51(10):1071-1076.   Published online October 15, 2008
Purpose : Respiratory syncytial virus (RSV) is the most frequent cause of lower respiratory infections in infants and young children. Early detection allows quarantining of infected inpatients to prevent nosocomial transmission and to choose a treatment. To achieve rapid reporting, to facilitate prompt antiviral therapy, and to avoid unnecessary use of antibiotics, an easy, rapid diagnostic method for RSV is...
Clinical Effects of Oseltamivir in Children with Influenza in Busan, in the First Half of 2004
Soo Kyoung Park, So Young Choi, Sung Mi Kim, Gil Heun Kim, Jin Hwa Jung, Im Jung Choi, Kyung Soon Cho
Clin Exp Pediatr. 2005;48(9):976-985.   Published online September 15, 2005
Purpose : Although influenza is one of the most important causes of acute respiratory tract infections in children, effective antiviral therapies are not common and there are only a few clinical studies on treatment of influenza in children. We evaluated the efficacy of oseltamivir in the treatment of naturally aquired influenza in children during the first half of 2004 in...
Retrospective Study for the Isolation of Influenza Virus and Prevalence Period in Busan from 2000 to 2002
Chang Hwan Oh, Byeong Hee Son, Ki Dae Kim, Jung A Lee, Sung Won Kim, Kyung Soon Cho
Clin Exp Pediatr. 2005;48(3):260-265.   Published online March 15, 2005
Purpose : During epidemics, influenza induces a high mortality and morbidity, and when influenza is prevalent, it is revealed by increased pneumonia, hospitalization due to influenza-like illness, and mortality in community. We aimed at the isolation of influenza virus and prevalence period in Busan from 2000 to 2002. Methods : For 3 years from 2000 to 2002, we analyzed the patterns...
A Clinical Study of Aseptic Meningitis in the Busan Area in 2002
Ji Hyun Park, Na Young Lee, Gil Hyun Kim, Jin Hwa Jung, Kyung Soon Cho, Sung Mi Kim
Clin Exp Pediatr. 2003;46(9):858-864.   Published online September 15, 2003
Purpose : There was a outbreak of aseptic meningitis in Busan, 2002. We report the clinical features and causative viruses. Methods : Two hundred seventy six children with aseptic meningitis who were admitted to the Department of Pediatrics, Maryknoll Hospital between January and December, 2002 were included. CSF, stool and throat swab viral cultures were done in 244 of these...