Clinical and Experimental Pediatrics

Original Article

Effect of endothelin receptor blockade on monocrotaline-induced pulmonary hypertension in rats

Kyoung Ah Lim, Jung Yun Shim, Sang Ho Cho, Kwan Chang Kim, Jae Jin Han, Young Mi Hong

Clin Exp Pediatr. 2009;52(6):689-695. Published online June 15, 2009

Purpose : To examine the effect of bosentan, a dual endothelin receptor (ER) antagonist, on the development of monocrotaline (MCT)-induced pulmonary hypertension in rats by especially focusing on the pulmonary vascular morphology changes. Methods : Sprague-Dawley rats were treated as follows: controls received a subcutaneous saline injection, MCT-treated rats received a subcutaneous MCT injection, and bosentan-treated rats received a MCT...

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Clinical Lecture

Pathology of Acquired Immunodeficiency Syndrome in Children

Sang Ho Cho

Clin Exp Pediatr. 1994;37(10):1474-1479. Published online October 15, 1994

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Case Report

Cushing’s Syndrome in Infancy

Pyung Kil Kim, Ki Sub Chung, Duk Jin Yun, Sang Hyon Suh, Sang Ho Cho

Clin Exp Pediatr. 1969;12(11):639-648. Published online November 30, 1969

There are little reports on the Cushing’s syndrome in children, especially in infancy in Korea. We have found recently a case of Cushing’s syndrome in infancy arising from a female infant. She has been complained from eleven month of age with general obesity including buffalo hump, excessive weight: gain, hirsutism and polyphgagia. Laboratory tests revealed that no thymic shadow in...

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