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A Case of leukemic Reticuloendotheliosis: A case report and literature review.

Se Ho Chang, Sun Ja Lee, Jong Hoon Park, Dong Hyuk Kum, Jung Dal Lee

Clin Exp Pediatr. 1979;22(11):996-1002. Published online November 15, 1979

Leukemic reticuloendotheliosis (L.R.E.) was first described as a clinical and pathological entity by Ewald in 1923. LRE is a rare neoplastic disease of the hematopoietic system that is characterized cliniclly by chronic course with an insidious onset. marked splenomegaly with absence of substantial lymphadenopathy and predominant in male and characterized histologically by the presence of circulating abnormal mononuclear cells with...

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