Clinical and Experimental Pediatrics

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Original Article

The relationship between catechol-O-methyltransferase gene polymorphism and coronary artery abnormality in Kawasaki disease

Hyo Jin Lee, Myung Sook Lee, Ji Sook Kim, Eun Ryoung Kim, Sung Wook Kang, Soo Kang Kim, Joo Ho Chun, Kyung Lim Yoon, Mi Young Han, Seong Ho Cha

Clin Exp Pediatr. 2009;52(1):87-92. Published online January 15, 2009

Purpose : Many gene polymorphisms are associated with coronary artery abnormalities in Kawasaki disease. Catechol-O- methyltransferase (COMT) plays an important role in the metabolism of catecholamines, catechol estrogen, and catechol drugs. Polymorphisms of the COMT gene are reported to be associated with myocardial infarction and coronary artery abnormalities. The aim of this study was to evaluate the relationship between COMT...

Clinical Studies of Henoch-Schölein Purpura Which was Considered as Acute Abdomen

Seong Young Jeong, Seong Yun Cho, Chio Heong Park, Seong Ho Cha, Byoung Soo Cho, Chang Il Ahn

Clin Exp Pediatr. 1993;36(8):1124-1132. Published online August 15, 1993

Henoch-Schölein purpura is a common pediatric disease presenting most frequently with skin, gastrointestinal, joint and renal manifestations. But in cases are infrequently only severe gastointestinal manifestations. It is hard to diagnose promptly and exactly. Clinical manifestations and laboratory findings were observed and analyzed in 20 cases with Henoch-Schölein purpura which were considered as acute abdomen, hospitalized at Kyung Hee university Hospital...

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