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Acanthosis nigricans is characterized by hyperpigmented, velvety thickening of the skin of any part of the body and frequently associated with internal malignancy, endocrine diseases and obesity. In children, systemic abnormality rarely occur in associated with prepubertal Acanthosis nigricans. We experienced a case of idiopathic Acanthosis nigricans, and made a brief review of literatures. |