Search

  • HOME
  • Search
Original Article
The relationship between catechol-O-methyltransferase gene polymorphism and coronary artery abnormality in Kawasaki disease
Hyo Jin Lee, Myung Sook Lee, Ji Sook Kim, Eun Ryoung Kim, Sung Wook Kang, Soo Kang Kim, Joo Ho Chun, Kyung Lim Yoon, Mi Young Han, Seong Ho Cha
Clin Exp Pediatr. 2009;52(1):87-92.   Published online January 15, 2009
Purpose : Many gene polymorphisms are associated with coronary artery abnormalities in Kawasaki disease. Catechol-O- methyltransferase (COMT) plays an important role in the metabolism of catecholamines, catechol estrogen, and catechol drugs. Polymorphisms of the COMT gene are reported to be associated with myocardial infarction and coronary artery abnormalities. The aim of this study was to evaluate the relationship between COMT...