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Original Article
DNA Methylation Change of IL-4 Gene from T Cell in Allergic Children
Jae Won Oh, Myung Gul Yum, Chang Ryul Kim, In-Joon Seol, Su A Shin, Ha Baik Lee, Se Jin Jang
Clin Exp Pediatr. 2005;48(6):634-639.   Published online June 15, 2005
Purpose : An understanding of the immunological process is required if primary prevention of atopic diseases is to be developed in early childhood. But, it is too hard to distinguish atopy from nonatopy under the age of two clinically, because the expression of phenotype and cytokines is vague in early childhood. We evaluated DNA methylation changes at Th2 interleukin-4 gene...
Elevated Circulating ICAM-1 and Eosinophil Cationic Protein in Children with Chronic Urticaria
You Sun Choi, Su A Shin, Young Dai Kim, Jae Won Oh, Ha Baik Lee
Clin Exp Pediatr. 2004;47(9):986-991.   Published online September 15, 2004
Purpose : Chronic urticaria is characterized by recurrent, itchy, and evanescent wheals over a period of six weeks. The mechanisms of chronic urticaria in children have not been fully elucidated. However, urticaria lesions represent a dynamic inflammatory process involving a complex interplay of various inflammatory mediators, chemokines, adhesion molecules and cellular interaction. The aim of this investigation was to elucidate...
Clinical Evaluation and Diagnosis of Children with Chest Pain
Su A Shin, Yong Joo Kim, Jae Whan Lee, Nam Su Kim, Soo Ji Moon
Clin Exp Pediatr. 2003;46(12):1248-1252.   Published online December 15, 2003
Purpose : Chest pain in the pediatric population is not rare and mostly benign. Causes of chest pain are diverse, and differential diagnosis is not easy. Chest pain in children is less likely to be cardiac in origin. Furthermore, chest pain in the pediatric population is rarely associated with life-threatening disease. This study was designed to evaluate children with chest...