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Original Article

Fas/FasL expression in the hippocampus of neonatal rat brains follwing hypoxic-ischemic injury

Young Pyo Chang, Myeung Ju Kim, Young Il Lee, Ik Je Im, Jae Ju Cho, Jong-Wan Kim, Sung Moon Yeo

Clin Exp Pediatr. 2006;49(2):198-202. Published online February 15, 2006

Purpose : Fas is a cell surface receptor that transduces apoptotic death signals. Interaction of extracelluar domain of Fas with Fas ligand(FasL) triggers the apoptotic process in many diseases. We investigated the expression of Fas and FasL in the hippocampus of 7-day-old newborn rat brains following hypoxia-ischemia injury. Methods : The 7-days-old newborn rats were exposed to 8 percent oxygen...

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