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Original Article

Infection

Viral load and rebound in children with coronavirus disease 2019 during the first outbreak in Daegu city

Mi Ae Chu, Yoon Young Jang, Dong Won Lee, Sung Hoon Kim, Namhee Ryoo, Sunggyun Park, Jae Hee Lee, Hai Lee Chung

Clin Exp Pediatr. 2021;64(12):652-660. Published online October 12, 2021

Web of Science 3 Crossref 4

Question: What is the natural course of viral load in children with coronavirus disease 2019 (COVID-19)?
Finding: A significant number of patients still had a relatively high viral load once clinically asymptomatic. Nearly half of the patients experienced viral rebound, which contributed to prolonged viral detection in their respiratory specimens.
Meaning: Further studies are needed to determine the clinical significance of viral rebound in asymptomatic or mild pediatric cases of COVID-19.

DOI: https://doi.org/10.3345/cep.2020.02033

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