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Review Article

Eosinophil-derived neurotoxin levels can predict allergic disease development and atopic march in children

Zak Callaway, Chang-Keun Kim

In some children, atopic manifestations begin with atopic dermatitis and progress to allergic asthma and allergic rhinitis; of them, a small subset experience food allergies as well. This progression shares genetic and environmental predisposing factors and immunological features, such as allergen-specific T helper type 2 responses, that manifest as specific immunoglobulin E production and eosinophil activation. Eosinophil-derived neurotoxin (EDN), which...

DOI: https://doi.org/10.3345/cep.2024.01382 [Accepted]

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