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Review Article

Malignancies in children who present with bone pain

Jun Ah Lee

Clin Exp Pediatr. 2008;51(8):792-796. Published online August 15, 2008

Bone pain in a child could be associated with cancer as an initial manifestation of the disease. The childhood malignancies that frequently present bone pain are leukemia, neuroblastoma, and primary bone tumors such as osteosarcoma and Ewing sarcoma. Persistent bone or joint pain associated with swelling, mass, or limitation of motion implies underlying serious causes. Systemic manifestations such as lymphadenopathy,...

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