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Original Article

An Experience of High Dose Intravenous Immunoglobulin Therapy in Refractory Evans Syndrome.

Hee Sup Kim, Won Sup Shin, Sang Il Lee, Sang Woo Kim

Clin Exp Pediatr. 1990;33(5):701-707. Published online May 31, 1990

Evans syndrome, a combination of autoimmune hemolytic anemia and idiopathic thrombocytopenic purpura, relapses freguently and is refractory to conventional treatment such as corticosteroid, immunosuppressive agents, splenectomy and plasma exchange. Recently Oda et al applied high dose immunoglobulin (400/kg/day for 4 days repeated 2 weeks later) to 5 month-old infant with refractory Evans syndrome, and was successful in maintaining remission for five years and nine...

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