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Original Article

Phenotypic and Functional Differentiation of Promyelocytic Cell Line HL-60 by N-N-dimethylformamide

Kyung Hyo Kim, Ju Young Seoh

Clin Exp Pediatr. 1998;41(4):481-488. Published online April 15, 1998

Purpose : HL-60 is a promyelocytic cell line. Fcγ receptors and complement receptor 3(CR3) play important role in the protective response of granulocytes and monocytes against microbial infection. We quantified the expression of FcγI, FcγII, FcγIII, and CD11b/CD18 during differentiation using HL-60 cells by N-N-dimethylformamide(DMF). Functional studies, such as phagocytic activity, respiratory burst and ADCC, were also performed. Methods : HL-60 cells were induced to...

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