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Original Article

Immunologic Changes of HL-60 Cells by Differentiation Inducing Agents I : Phenotypic Differentiation of FcγR and Mac-1

Hye Soon Kim, Kyung Hyo Kim, Gyoung Hee Kim, Ju Young Seoh

Clin Exp Pediatr. 1998;41(10):1342-1350. Published online October 15, 1998

Purpose : Fc receptors and Mac-1 play an important role in the protective response of granulocytes and monocytes against microbial infection. FcγRⅠ, FcγRⅡ, FcγRⅢ as well as CD11b/ CD18 have never been measured in a quantitative way during hemopoiesis. Thus we quantified the expression of FcγRⅠ, FcγRⅡ, FcγRⅢ, and CD11b/CD18 during hematopoietic differentiation using HL-60 cells, which was induced to...

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