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Original Article

Study on Hepatitis B Virus Pre-S/S Gene Mutations in Children with Chronic Hepatitis B Infection

Byeong Hee Son, Yeong Hong Park, Woo Yeong Chung

Clin Exp Pediatr. 2001;44(7):741-751. Published online July 15, 2001

Purpose : Hepatitis B virus(HBV) with various mutations has been reported. The aims of this study were to investigate the frequency and manifestation of HBV pre-S/S mutations in children with chronic hepatitis B infection. Methods : Sera from 17 children with chronic hepatitis B infection were analyzed by direct sequencing of polymerase chain reaction amplification of HBV DNA. Results : Seventeen...

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