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Original Article
Histiocytic Medullart Reticuloisis in Children.
Duck Kyu Kim, Jung Hyun Park, Ok Ji Hwang, Ja Ye Kim, Woo Kap Chung, Kye Sook Lee
Clin Exp Pediatr. 1988;31(9):1217-1224.   Published online September 30, 1988
Histiocytic medullary reticulosis (HMR) is a clinicopathologic syndrome characterized by its acute onset and relentless progression to death within a few months. Major clinical features are fever, wasting, generalized lymphadenopathy and hepatosplenomegaly. In the terminal stages, Jaundice, purpura, anemia and leukopenia are common. Cardinal pathologic features are diffuse proliferation of atypical, neoplastic, erythrophagocytic histiocytes and their precursors throughout the reticuloen- dothelial system. Here, we present 2...
Case Report
A Case of Histiocytic Medullary Reticulosis in 17 Month-old Child.
Oh Kyung Lee, Wan Seob Kim, Myung Ho Lee, Sung Seek Lee, Sook Ja Park
Clin Exp Pediatr. 1983;26(12):1220-1225.   Published online December 31, 1983
Histiocytic medullary reticulosis(HMR) is a rare, uniformly fatal, acute disease of the reticuloen dothelial system. Major features are fever, malaise, weakness, weight loss, lymphadenopathy, hepatosplenomegaly, jaundice and purpura. Common laboratory finding is severe pancytopenia. Cardinal pathologic feature is proliferation of atypical, neoplastic, erythrophagocytic histiocytes. Recently we experienced a case of HMR in 17 month-old male child. The clinical findings and...
Original Article
Histiocytic Medullary Reticulosis in Children: Report of Four Cases and Analysis of Previously Reported Cases.
Eue Cho Yang, Jae Ho Lee, Soon Ung Kang, Hyo Seop Ahn, Chang Yee Hong, Je G Chi, Yong Il Kim
Clin Exp Pediatr. 1981;24(10):928-941.   Published online October 15, 1981
Histiocytic Medullary Reticulosis(H.M.R.) is a rapidly progressing fatal disease seen most often in adults, but it has been reported in children younger than 15 years of age. H.M.R. is clinically characterized by fever, wasting generalized lymphadenopathy and hepatosplenomegaly. In the terminal stage, jaundice, purpura, anemia and pancytopenia are all present with or without skin involvement. Cardinal pathologic features are systemized...