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Histiocytic medullary reticulosis(HMR) is a rare, uniformly fatal, acute disease of the
reticuloen dothelial system. Major features are fever, malaise, weakness, weight loss,
lymphadenopathy, hepatosplenomegaly, jaundice and purpura. Common laboratory finding is severe pancytopenia. Cardinal pathologic feature is proliferation of atypical, neoplastic, erythrophagocytic
histiocytes. Recently we experienced a case of HMR in 17 month-old male child. The clinical findings
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