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Original Article
Surfactant Protein SP-A, B, and C: Purification and Biochemical Characterization
Chong-Woo Bae, Yong-Mook Choi, Joo Hyun Kang, Kil Lyong Kim, Kyung Soo Hahn
Clin Exp Pediatr. 1996;39(2):218-229.   Published online February 15, 1996
Purpose : Several kinds of exogenous pulmonary surfactants (SF), either synthetic or animalderived, are being used for the replacement therapy in respiratory distress syndrome (RDS) of newborn, especially in premature infants, and improved the neonatal mortality and morbidity. Because synthetic preparations are lack of surfactant protein (SP) and animal-derived preparations cause immunogenecity of heterogenous SP, there have been great necessity for the development of next...
Clinical and Ultrasonographic Study on Prenatal Brain Damage in Newborn Infants
Kook In Park, Dong Gwan Han, Ran Namgung, Chul Lee
Clin Exp Pediatr. 1994;37(10):1364-1375.   Published online October 15, 1994
To determine the incidence of prenatal brain damage, and evaluate the clinical and neurosonographical characteristics, we prospectively examined 508 newborn infants with intracranial ultrasound within the first day of life who admitted to the NICU of Severance Hospital from June 1990 to January 1992 and reviewed maternal or neonatal medical records. We found 12 cases(2.4%) of fetal brain...
Study on the Temperature Measurement in the Newborn Infants.
Eun Saing Jee, Young Pyo Chang, Jung Hwan Choi, Chong Ku Yun, Yong Ran Kim, Myoung Sook Lee
Clin Exp Pediatr. 1989;32(12):1632-1636.   Published online December 31, 1989
We measured body temperatures and stabilization times of 100 term and 52 preterm infants at four sites. The sites were core, aural, rectal and axilla in order of degree of temperature. There was significant difference between term and preterm infants (term infant higher, p<0.001). Mean difference between axillary and rectal temperatures was 0.501C(rectal higher). Mean difference between rectal and core temperatures was 0.10lC(core higher)....
A Study on Serum Ca, P, Mg, Parathyroid Hormone, Calcitionin, and 1, 25-dihydroxyvitamin D Concentrations in Normal Newborn and Low Birth Weight Infants.
In Bock Lee, Chang Soo Ra
Clin Exp Pediatr. 1987;30(6):613-624.   Published online June 30, 1987
Early neonatal hypocalcemia occurs within the first few days of life, with the lowest concentrations of serum calcium being reached at 24 to 48 hours of age. An infant can be considered to be hypocalcemic when serum calcium concentrations are below 7 mg/dl or when ionized calcium concentrations are below 3 to 3.5 mg/dl. The most commonly encountered causes of neonatal hypocalcemia are prematurity,...
A Study of Blood Pressure Measurement in Newborn Infants.
Yoon Deok Kim, Joong Whan Choi, Chong Ku Yun
Clin Exp Pediatr. 1986;29(8):819-829.   Published online August 31, 1986
The inability to detect Korotkoff sounds in infants have in the past made it difficult for most pediatricians to measure blood pressures by indirect conventional sphygmomanometry. Now, however, Korotkoff sounds, or the mechanical events which produce them, can be sensed with an ultrasonic Doppler device. The author measured systolic and diastolic blood pressure using a Doppler arteriokinetog raphic instrument during 6...
A Study on Plasma Antidiuretic Hormone and Serum Sodium Levels of Cord Blood in the Newborn Infants.
Choon Ho Park, Chang Soo Ra
Clin Exp Pediatr. 1986;29(7):748-757.   Published online July 31, 1986
The authors studied the plasma antidiuretic hormone levels of cord blood in 40 cases of newborn infants and also studied the serum sodium levels of cord blood in 40 cases of newborn infants. For the purpose of analysis, the study subjects were divided into four group; 1st group of 17 cases of vaginal delivery infants with fetal distress, 2nd group...
A Study on Serum Immuoglobulins and Complements in Newborn Infants.
Song Soo Moon, Chang Soo Ra
Clin Exp Pediatr. 1986;29(1):58-71.   Published online January 31, 1986
The author investigated serum immunoglobulins (IgG, IgA, and IgM) and complements (C3and C4) of cord blood in 29 cases of normal fullterm infants, 14 cases of low birth weight infants (8 cases of premature infants) and 43 cases of their mothers at delivery. Serum immunoglobulin and complement levels were measured by the single radial immuno diffusion method (NISSUI, Japan). The...
A study on Glucose Metabolism in Newborn Infants.
Keun Chul Myung, Chang Soo Ra
Clin Exp Pediatr. 1985;28(12):1167-1176.   Published online December 31, 1985
Glucose metabolism in newborn infants has not been clearly defined. A thorough understanding of the physiology of glucose metabolism between mother and newborn infants is necessary in the evaluation of the newborn infant with hypoglycemia. Author studied the serum glucose, insulin, cyclic AMP and glucagon levels in 27 pairs of cord blood in newborn infant and maternal blood at paturition....
A Study on Calcium Metabolism in Newborn Infants.
Jin Heon Kim, Chang Soo Ra
Clin Exp Pediatr. 1985;28(10):967-976.   Published online October 31, 1985
A thorough understanding of calcium homeostasis and metabolism in newborn infants is necessary in the evaluation of any newborn infant with hypocalcemia. Author studied the levels of urinary calcium and phosphorus during the 48 hours after birth, and also studied before and after feeding during the 24 hours after birth in 19 normal term infants. And serum calcium, phosphorus, parathormone,...
A Study on Serum Creatinine and BUN Levels in Newborn Infants.
Shin Chung Jee, Chang Soo Ra
Clin Exp Pediatr. 1985;28(8):741-750.   Published online August 31, 1985
The concept of renal function in the neonate has been that the developing kidney is immature and that glomerular and tubular functions are low for body size as compared with the adult. Authors determined the serum creatinine and blood urea nitrogen (BUN) levels of cord blood in 57 newborn infants(42 normal full-term and 15 premature infants) with gestational age of...
Urine Sediments and Protein in Healthy Newborn Infants.
Jeh Hoon Shin, Eui Soo Park, Woo Gill Lee, Chong Moo Park
Clin Exp Pediatr. 1983;26(12):1159-1167.   Published online December 31, 1983
h7Routine urine examination in neonatal period is one of the most basic laboratory examination for early diagnosis of various diseases such, as urinary tract infection, congenital anomalies, and renovascular disorders etc. There are many methods to collect urine, but each of these methods has a problem, that is, catheterization causes urethral injury and ascending infection; suprapublic puncture is the most...
A Study of Serum Albumin, Globulin, Total Protein, and A/G Ratio in Korean Mothers and Newborn Infants.
Keun Chul Myoung, Chang Soo Ra
Clin Exp Pediatr. 1981;24(11):1039-1045.   Published online November 15, 1981
With the availability of the method of analysis of serum protein using minute amounts of material, it was felt desirable to understand the protein metabolism and physiologic function in the body. The present study was undertaken to clarify the serum albumin, globulin and total protein at term to demonstrate the normal concentration and correlation between the 30 mother and newborn...