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Original Article

Assessment of Endogenous Nitric Oxide Formation in the Neonate : Measurement of Urinary Nitrite and Citrulline Concentrations

Young Ho Kim, Ki Hwan Yu, Young Sook Hong, Sun Kyum Kim

Clin Exp Pediatr. 2001;44(1):40-45. Published online January 15, 2001

Purpose : At birth, as the fetus adjusts to the “new world”, the fetal pulmonary circulation undergoes a striking transition, characterized by an immediate rise in pulmonary blood flow and a sustained decrease in pulmonary vascular resistance(PVR). In the factors which reduce PVR after birth, are ventilation of the lung by gas, increase of oxygen tension in pulmonary vascular system,...

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