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Original Article

Gastroenterology

Efficacy and safety of carbon dioxide versus room-air insufflation in pediatric colonoscopy: a randomized controlled trial

Ajay Aravind, Ujjal Poddar, Anshu Srivastava, Moinak Sen Sarma

Clin Exp Pediatr. 2025;68(8):594-600. Published online March 11, 2025

CO₂ insufflation has been used instead of air insufflation to reduce postprocedure pain and discomfort in adults; however, adequately powered studies in children are scarce. This randomized controlled trial of 200 children showed that CO₂ insufflation reduces postprocedure pain and discomfort during pediatric colonoscopy with no signs of CO₂ retention. CO₂ insufflation is safe and causes less pain in children.

DOI: https://doi.org/10.3345/cep.2024.02012

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