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Review Article
Efficacy and effectiveness of extended-valency pneumococcal conjugate vaccines
Hyunju Lee, Eun Hwa Choi, Hoan Jong Lee
Clin Exp Pediatr. 2014;57(2):55-66.   Published online February 24, 2014

The 7-valent pneumococcal protein conjugate vaccine (PCV7) has been shown to be highly efficacious against invasive pneumococcal diseases and effective against pneumonia and in reducing otitis media. The introduction of PCV7 has resulted in major changes in the epidemiology of pneumococcal diseases. However, pneumococcal vaccines induce serotype-specific immunity, and a relative increase in non-vaccine serotypes has been reported following the...

Original Article
Antibody response to pneumococcal vaccination in children with chronic or recurrent rhinosinusitis
Ji Hyeon Baek, Hyun Kyong Seo, Hye Mi Jee, Youn Ho Shin, Man Yong Han, Eun Sang Oh, Hyun Ju Lee, Kyung Hyo Kim
Clin Exp Pediatr. 2013;56(7):286-290.   Published online July 19, 2013
Purpose

Although chronic and recurrent rhinosinusitis is prevalent in children, little is known about its causes. Here, we investigated the humoral immunity in children with chronic or recurrent rhinosinusitis.

Methods

We examined 16 children attending the outpatient clinic at the CHA Bundang Medical Center including 11 boys and 5 girls, aged 3.11 years (mean age, 5.6 years), who had rhinosinusitis for >3 months...

Functional Antibody Responses to Seven Serotypes in Pneumococcal Polysaccharide Vaccine in Children
Ji Hye Park, Hee Jung Kim, Young Mi Hong, Kyung Hyo Kim
Clin Exp Pediatr. 2004;47(11):1173-1180.   Published online November 15, 2004
Purpose : Streptococcus pneumoniae is an important pathogen in children as well as in elderly people. The aim of this study was to assess the opsonization activity of pneumococal capsular antibody to seven serotypes in 23-valent pneumococcal polysaccharide vaccine before and after immunization in Korean children. Methods : Nine children from 24 to 49 months of age were immunized with 23-valent...