Clinical and Experimental Pediatrics

Original Article

Clinical Spectrum and Lung Pathology in Children with Interstitial Lung Disease

Ji-Hyun Chung, Seung-Ju Ha, Bong-Seong Kim, Soo-Jong Hong

Clin Exp Pediatr. 2002;45(1):79-87. Published online January 15, 2002

Purpose : Interstitial lung disease(ILD) is a rare and poorly characterized disorder in children with poor prognosis. To understand the ILD in children, we reviewed our experience with 21 patients who were diagnosed interstitial lung disease during 9-year period at Asan Medical Center retrospectively. Methods : Severity-of-illness score was measured by the Denver protocol. We evaluated underlying diseases, clinical manifestations, high resolution computed tomography findings,...

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Treatment of Intravenous Immune-Globulin Resistant Kawasaki Disease with Corticosteroids

Dae-Eui Hong, Kyung-Yil Lee, Ji-Whan Han, Sung-Soo Hwang, Kyong-Su Lee

Clin Exp Pediatr. 1997;40(10):1453-1457. Published online October 15, 1997

Purpose : To evaluate the efficacy of steroid therapy on prevention of development and progression of coronary artery aneurysm in intravenous immune globulin(IVIG)-resistant Kawasaki disease, we treated three children with high dose of intravenous methylprednisolone followed by low dose oral prednisolone. Methods : We selected three children with Kawasaki disease who did not repond or who initially responded but soon developed recrudescent fever after retreatment...

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Case Report

A Case of Chronic Active Hepatitis.

H J Park, H K Park, H J Chun, M J Shin, S C Kang

Clin Exp Pediatr. 1981;24(10):991-996. Published online October 15, 1981

Chronic active hepatitis (CAH) is defined as ongoing inflammation within the liver sustained beyond the expected time of resolution. The etiology of CAH is not completely understood, but hepatitis B infection, drugs such as oxyphenisatin, isoniazid, and alpha-methyldopa, and altered immunity are considered. The most common findings are jaundice, hepatosplenomegaly, elevated serum transaminase activities, hypergammaglobulinemia, and positive "autoimmune" serologic tests,...

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